
CACHE Design Case Studies
CACHE Process Design Case Study Vol. 4"Alternative Fermentation Processes for Ethanol Production"The objective of this case study is the preliminary design and economic evaluation of a fermentation process for the production of ethanol from a molasses feedstock. The intent is to expose the student to some non-traditional chemical engineering processes and to the expanding field of biotechnology. The scope of the study is such that groups of 2-3 students should be able to complete the design in about 30 days. The major focus of this design is the creation and rational development of a suitable process flowsheet, simulation of the flowsheet by the simulator FLOWTRAN, and economic evaluation and cost minimization of the final process.The problem begins with the specification of the plant operating requirements. The type of fermentor to be used as well as plant operating conditions are left open. Suggested fermentors include batch, CSTR, CSTR w/cell recycle as well as a novel extractive fermentor based on the use of hollow fiber membranes (HFEF). The choice of the fermentor will affect the nature of the flowsheet and lead to several design alternatives which the students will have to screen before arriving at a workable flowsheet that is ready for simulation. This case study includes a floppy disk with input files for the simulator FLOWTRAN as well as a program written in BASIC to evaluate the performance of CSTR fermentors. The problem statement was posed by Professors Steven LeBlanc and Ronald L. Fournier and prepared under their supervision by the student Samer Naser at the University of Toledo. CACHE Process Design Case Study Vol. 5"Retrofit of a Heat Exchanger Network and Design of a Multiproduct Batch Plant"This volume contains two short design projects that can be developed by groups of 2-3 s tudents in about two weeks. As opposed to the large projects that are commonly used in a design course, the objective of the case study is to expose students to a greater variety of problems and which are of current industrial significance.The f irst problem deals with the retrofit of a heat exchanger network consisting of 8 exchangers with 5 hot and 3 cold processing streams as well as steam and cooling water. The layout of the network and areas of the exchangers are also given. The objective is to determine a retrofit design that can reduce the energy consumption within specified limits for the capital investment and payout times. This problem requires examination of alternatives for the level of energy recovery, matching of streams, addition o f area, and removal or reassignment of existing exchangers and piping. This problem can be used to illustrate basic concepts of heat integration, as well as the application of computer software such as Target II, THEN, MAGNETS and RESHEX. The second desig n problem deals with the design of a batch processing plant that has to manufacture 4 different products, all of which require 5 similar processing steps (reaction, product recovery, purification, crystallization and centrifuge). An important aspect of th is problem is that the production schedule and inventory must be anticipated at the design stage. Furthermore, this problem also requires analyzing alternatives for merging processing tasks into single units, and using parallel units with and without intermediate storage. The use of Gantt charts is emphasized to examine some of these alternatives. The case study also includes two sets of homework problems with solutions that can be used to provide the basic background for the two problems. This case study has been prepared by the students Richard Koehler and Brenda Raich at Carnegie Mellon University under the supervision of Professor Grossmann who developed the problem statements and educational material. CACHE Process Design Case Study Vol. 6"Chemical Engineering Optimization Models with GAMS"The objective of this case study is to provide a set of chemical engineering problems to supplement optimization courses at both the undergraduate and graduate level. This case study should also be useful in other courses and to practicing engineers to learn about GAMS and its applications.GAMS is an algebraic modelling system in which the user need not be concerned with details of providing the interfaces with various optimization codes. Instead, the GAMS environment allows the user to concentrate on the modelling of problems, which u ltimately is the main skill that is required for the successful application of optimization in practice. This case study covers applications at various levels of complexity in the following areas: (a) Planning and scheduling of batch and continuous proce sses, (b) Chemical and phase equilibrium, (c) Design of heat exchanger networks, distillation columns and batch processes, (d) Synthesis of reaction paths, heat exchanger networks and distillation sequences, (e) Optimization of dynamic and distributed par ameter models. These problems are modelled as linear, nonlinear and mixed-integer optimization problems. This case study describes in detail the formulation and solution of a total of 22 optimization problems that cover the different areas cited above. Exercises are also given for each problem. In addition, the case study includes:
CACHE Process Design Case Study Vol. 7"Design of an Ethylbenzene Production Plant- Preliminary Design and Economic Analysis"The objective of this case study is the preliminary design and economic evaluation of an alkylation process for the production of ethylbenzene from ethylene and benzene. The intent is to expose the student to a traditional chemical engineering process. The scope of the study is such that groups of 3-4 students should be able to complete the design in 3 months. The major focus of this design is the creation and development of a suitable process flowsheet, simulation of the flowsheet by the simulator HYSYS, economic evaluation and cost minimization, and HAZOP analysis of the final process. The problem begins with a statement of the design specifications. Students are then required to consider alternatives for the reactor type (fixed or fluidized bed), reactor conditions (liquid or vapor phase) and separation scheme. These choices affect the layout of the flowsheet and lead to several design alternatives. Students are expected to analyze the various process alternatives based on economic, safety, and environmental factors. Included in this case study is a floppy disk containing the HYSYS simulation file and GAMS input files for modeling the heat integration. The problem statement was posed by Professor Costas D. Maranas and prepared by James E. Lease, Gregory L. Moore, Ryan M. Scofield and Joseph D. Sevick in the department of Chemical Engineering at the Pennsylvania State University. Mike Kalp was also involved in putting the case study together, and he was supported by the ECSEL program at Pennsylvania State University.
This case study is available in two forms:
CACHE Supporting department $50 Non-supporting department $90 b. CD-ROM containing text of case study and HYSIS file. Large flowsheet diagram is also provided. CACHE Supporting department $30 Non-supporting department $50
CACHE Process Design Case Study Vol. 8"Nitrogen from Air" (on-line version available at no cost)
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