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Adaptive
Immunity by Utilization of High Throughput Technologies," Curr
Opin.Biotechnol. 22: 584-9 (2011) PMID:21570821.
- Makino T. Skretas, G. and G. Georgiou, "Strain
Engineering
for
Improved Expression of Recombinant Proteins In Bacteria," Microbial
Cell Factories 10:32 (2011) PMID:21569582
- Feeney, M.A., Veeravalli, K., Boyd, D., Gon, S.,
Faulkner,
M.J.,
Georgiou, G. & Beckwith. J., "Rewiring MajorElectron Flow
Pathways in E.coli
by a Single Amino Acid Change in Lipoamide
Dehydrogenase" Proc. Natl Acad Sci USA 108:7991-6.
(2011) PMID:21521794
- Jung, S.T., Kang, T.H., Kelton, W. and G. Georgiou,
"Bypassing
Glycosylation: Engineered Aglycosylated Full Length IgG for Human
Therapy," Curr Opin.Biotechnol. (in press)
PMID:21420850
- Cantor J., Stone, E.M. and G. Georgiou, "Expression
and
Biochemical
Characterization of the Human Enzyme N-Terminal Asparagine
Amidohydrolase (hNTAN1)" Biochemistry 50:3025-33
(2011). PMID:21375249
- Cantor J., Yoo, T.H., Dixit, A., Iverson, B.L.,
Forsthuber,
T.
and G,
Georgiou "Therapeutic Enzyme Deimmunization by Combinatorial T-Cell
Epitope Removal Using Neutral Drift" Proc. Natl. Acad. Sci.
USA
108:1272-77 (2011). PMID:21209329
- Veeravalli, K., Boyd, D., Iverson, B.L., Beckwith, J.
and
G.
Georgiou,
"Laboratory Evolution of Glutathione Biosynthesis Reveals Natural
Compensatory Pathways," Nature Chem. Biol. 7:101-105
(2011) PMID:
21186348.
- Stone, E.M., Chantranupong, L., and G. Georgiou, "The
Second
Shell
Metal Ligands of Human Arginase Affect Coordination of Nucleophile and
Substrate" Biochemistry 49:10582-8
(2010) PMID: 21053939
- Makino, T., Skretas, G., Kang, T.-H. and G. Georgiou,
"Comprehensive
engineering of Escherichia
coli for enhanced expression of IgG
antibodies," Metabolic Eng. 13: 241-51 (2010)
PMID:21130896
- Reddy, S.T., Ge, X., Miklos, A.E., Hughes, R.A. Kang.
S-H.,
Hoi, K.-H.,
Chrysostomou. C., Hunicke-Smith, S., Iverson, B.L., Tucker, P.W.,
Ellington, A.D. & G. Georgiou, " Isolation of Monoclonal
Antibodies Without Screening by Mining the Variable Gene Repertoire of
Plasma Cells," Nature Biotechnol. 28:965-9
(2010). PMID: 20802495
• Leading Edge Select: Cell 143:491
(2010)
• "Better Antibodies Through Sequencing" Biotechniques
http://www.biotechniques.com/news/Better-monoclonals-through-sequencing/biotechniques-303792.html
- Qiu, J.K., Jung, S.T., Georgiou, G. and H.Y. Hang,
"Enrichment
of
Escherichia
coli
Spheroplasts Displaying scFv Antibodies Specific for
Antigens Expressed on the Human Cell Surface," Appl Microbiol
Biotechnol. 88:1385-91 (2010) PMID:
20878322
- Skretas G. and G. Georgiou, "A Simple Genetic
Selection for
the
Isolation of Overexpressed Genes that Enhance the Accumulation of
Membrane-Integrated Human G Protein-Coupled Receptors in Escherichia
coli" Appl. Environ. Microbiol 76:5852-9
(2010) PMID: 20639362
- Jung S.-T., Kang T.-H., and G. Georgiou "Efficient
Expression
and
Purification of Human Aglycosylated Fcγ receptors in Escherichia coli,"
Biotechnology & Bioengineering 107:21-30
(2010) PMID: 20506277
- Mazor, Y., Van Blarcom, T., Carroll, S., and G.
Georgiou,
"Selection of
full-length IgGs by tandem display on filamentous phage particles and
Escherichia
coli
fluorescence-activated cell sorting screening," FEBS
J. 277:2291-303 (2010) PMID: 20423457
- Ge, X., Mazor, Y., Hunicke-Smith S. P. Ellington A.D.
and
G.
Georgiou,
"Rapid Construction and Characterization of Synthetic DNA libraries
Without DNA Amplification," Biotechnology &
Bioengineering
106:347-57 (2010) PMID: 20198660
- Van Blarcom T, Sofa-Podesta, C., Ang J., Boyer, J.L.,
Crystal,
R. and G. Georgiou "Affinity Maturation of an
Anti-V Antigen IgG Expressed In Situ Via Adenovirus Gene Delivery
Confers Enhanced Protection Against Yersinia pestis
Challenge" Gene
Therapy 17:913-21 (2010) PMID: 20393511
- Stone, E.M., Chantranupong, L, Glazer S.E, Cherukuri,
P.,
Breece, R.M., Tierney D.L., Curley S.A. and G. Georgiou, "Replacing Mn+2
with Co+2 in Human Arginase I Enhances
Cytotoxicity Towards L-Arginine Auxotrophic Cancer Cell Lines" ACS
Chemical Biology 5:333-42 (2010) PMID:
20050660
- Jung, S.T., Reddy, S., Kang, T.H, Borrok, J.M.,
Sandlie,
I.,
Tucker, P.W. and G. Georgiou, "Aglycosylated IgG Variants Expressed in E.
coli that Selectively Bind FcγRI
Potentiate Tumor Cell Killing by Monocyte-Derived Dendritic Cells," Proc
Natl Acad Sci U S A 107:604-9 (2010)
PMID: 20080725
- Research Highlight: Nature Biotechnol.
28:45
(2010)
- Commentary by Osherovich, L. SciBX
3
(2010) doi:10.1038
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